Can morning light and melatonin double the power of antidepressants?

This trial tests whether adding two 'chronotherapeutics'—bright light therapy in the morning and a slow-release melatonin pill at night—to standard antidepressants can better ease depression in adults who also have insomnia. About 184 people with major depression and sleep problems will receive these add-ons, alone or together, for 8 weeks. The goal is to see if this combination reduces depressive symptoms more than antidepressants alone, potentially offering a new strategy for the many patients who don't fully respond to medication.