500,000-Patient study aims to unlock secrets of chronic liver disease
NCT ID NCT05744713
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study will follow up to 500,000 adults with chronic liver disease or cirrhosis to understand how the disease progresses and how treatments are used in everyday practice. Researchers will collect data from medical records and patient reports to improve care and outcomes. No new treatments are being tested; instead, the goal is to gather real-world evidence to guide future care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could provide valuable insights into how chronic liver disease progresses and how current treatments work in real-world settings.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test new therapies. Results may take years and might not lead to immediate changes in care.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atrium Health Center for Liver Disease and Transplant
Charlotte, North Carolina, 28204, United States
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Baylor College of Medicine
Houston, Texas, 77021, United States
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Baylor Scott & White Research Institute
Dallas, Texas, 75246, United States
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Columbia University Irving Medical Center/ New York Presbyterian Hospital
New York, New York, 10032, United States
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Georgetown Medstar Transplant Institute
Washington D.C., District of Columbia, 20007, United States
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Keck School of Medicine of USC
Los Angeles, California, 90033, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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Stanford Medicine
Redwood City, California, 94063, United States
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Temple University - Lewis Katz School of Medicine
Philadelphia, Pennsylvania, 19140, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States