New shot combo aims to silence hepatitis b virus

NCT ID NCT07245953

First seen Dec 10, 2025 · Last updated May 14, 2026 · Updated 25 times

Summary

This study tests two experimental injections, HT-101 and HT-102, in 60 adults with chronic hepatitis B. The goal is to see if the combination can lower the virus to undetectable levels and keep it under control. Participants must already be on standard antiviral therapy. The trial is double-blind and placebo-controlled, meaning some receive the real treatment and some a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beijing Ditan Hospital Capital Medical University

    Beijing, Beijing Municipality, 100015, China

  • Guangzhou Eighth People's Hospital, Guangzhou Medical University

    Guangzhou, Guangdong, 510440, China

  • Henan Infectious Diseases Hospital , The Sixth People's Hospital of Zhengzhou

    Zhengzhou, Henan, 450000, China

  • Mengchao Hepatobiliary Hospital of Fujian Medical University

    Fuzhou, Fujian, 350028, China

  • Nanchang Ninth Hospital

    Nanchang, Jiangxi, 330022, China

  • Nanfang Hospital

    Guangzhou, Guangdong, 510515, China

  • Qingyuan People's Hospital

    Qingyuan, Guangdong, 511518, China

  • Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine

    Nanning, Guangxi, 530011, China

  • Shanghai Public Health Clinical Center

    Shanghai, Shanghai Municipality, 200083, China

  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan, 610072, China

  • The Second Hospital of Nanjing

    Nanjing, Jiangsu, 210003, China

  • Zhenjiang Third People's Hospital (Zhenjiang Infectious Diseases Hospital)

    Zhenjiang, Jiangsu, 212021, China

Conditions

Explore the condition pages connected to this study.