New cough drug shows promise in early trial

NCT ID NCT05660850

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tested an experimental drug called GDC-6599 in 49 adults with long-term cough that doesn't go away with standard treatments. The goal was to see if the drug could reduce how often people coughed and how bad the cough felt. Participants took the drug or a placebo for a period, then switched, and their cough was recorded with a special device. The study is complete, and results will help decide if larger trials are needed.

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Contacts and locations

Locations

  • ADAC Research PA

    Greenville, South Carolina, 29607, United States

  • Belfast City Hospital

    Belfast, BT9 7AB, United Kingdom

  • Bellingham Asthma, Allergy & Immunology

    Bellingham, Washington, 98225, United States

  • California Medical Research Associates, Inc.

    Northridge, California, 91324, United States

  • Castle Hill Hospital

    Cottingham, North Humberside, HU16 5JQ, United Kingdom

  • Clinical Research Associates Of Central Pa , Llc

    DuBois, Pennsylvania, 15801-2277, United States

  • Diex Recherche - Québec - HyperCore - PPDS

    Québec, Canada

  • Glenfield Hospital

    Leicester, LE3 9QP, United Kingdom

  • Kings College Hospital

    London, SE5 9RS, United Kingdom

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • McMaster University Medical Centre

    Hamilton, Ontario, L8N 3Z5, Canada

  • Pharmaceutical Research & Consulting, Inc.

    Dallas, Texas, 75231, United States

  • Pioneer Clinical Studies

    Coral Gables, Florida, 33134, United States

  • Queen Anne Street Medical Centre

    London, W1G 8HU, United Kingdom

  • Royal Infirmary of Edinburgh

    Edinburgh, EH16 4SA, United Kingdom

  • Southern California Institute For Respiratory

    Los Angeles, California, 90048, United States

  • TrialsWest Pty Ltd

    Spearwood, Western Australia, 6163, Australia

  • West Walk Surgery

    Bristol, BS37 4AX, United Kingdom

Conditions

Explore the condition pages connected to this study.