New drug shows promise for chronic cough sufferers

NCT ID NCT05660850

First seen Jan 05, 2026 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tested an experimental drug called GDC-6599 in 49 adults with chronic cough that didn't improve with standard treatments. Participants took either the drug or a placebo, then switched after a period. The main goal was to see if the drug reduced how often people coughed over 24 hours, measured by a special recording device. The study also checked for side effects and how participants rated their cough severity.

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Contacts and locations

Locations

  • ADAC Research PA

    Greenville, South Carolina, 29607, United States

  • Belfast City Hospital

    Belfast, BT9 7AB, United Kingdom

  • Bellingham Asthma, Allergy & Immunology

    Bellingham, Washington, 98225, United States

  • California Medical Research Associates, Inc.

    Northridge, California, 91324, United States

  • Castle Hill Hospital

    Cottingham, North Humberside, HU16 5JQ, United Kingdom

  • Clinical Research Associates Of Central Pa , Llc

    DuBois, Pennsylvania, 15801-2277, United States

  • Diex Recherche - Québec - HyperCore - PPDS

    Québec, Canada

  • Glenfield Hospital

    Leicester, LE3 9QP, United Kingdom

  • Kings College Hospital

    London, SE5 9RS, United Kingdom

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • McMaster University Medical Centre

    Hamilton, Ontario, L8N 3Z5, Canada

  • Pharmaceutical Research & Consulting, Inc.

    Dallas, Texas, 75231, United States

  • Pioneer Clinical Studies

    Coral Gables, Florida, 33134, United States

  • Queen Anne Street Medical Centre

    London, W1G 8HU, United Kingdom

  • Royal Infirmary of Edinburgh

    Edinburgh, EH16 4SA, United Kingdom

  • Southern California Institute For Respiratory

    Los Angeles, California, 90048, United States

  • TrialsWest Pty Ltd

    Spearwood, Western Australia, 6163, Australia

  • West Walk Surgery

    Bristol, BS37 4AX, United Kingdom

Conditions

Explore the condition pages connected to this study.