Stroke breakthrough? drug plus clot removal may boost recovery

NCT ID NCT05797792

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 31 times

Summary

This study tests whether giving a clot-dissolving medicine directly into the brain artery, right after mechanical clot removal, helps people recover better from a severe stroke. About 440 adults with large-vessel blockage will be randomly assigned to get the extra drug or not. The goal is to see if more patients achieve near-normal function at 90 days.

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Contacts and locations

Locations

  • Hospital Clinic Barcelona

    Barcelona, Spain, 08014, Spain

  • Hospital Germans Trías i Pujol

    Badalona, Spain, Spain

  • Hospital Josep Trueta

    Girona, Spain, Spain

  • Hospital Universitario Central de Asturias

    Oviedo, Spain, Spain

  • Hospital Universitario Dr. Balmis

    Alicante, Spain, Spain

  • Hospital Universitario Son Espases

    Palma de Mallorca, Spain, Spain

  • Hospital Universitario Virgen de la Arrixaca

    Murcia, Spain, Spain

  • Hospital Universitario de A Coruña

    A Coruña, Spain, Spain

  • Hospital Universitario de Cruces

    Bilbao, Spain, Spain

  • Hospital Universitario de Donostia

    San Sebastián, Spain, Spain

  • Hospital Universitario de Navarra

    Pamplona, Spain, Spain

  • Hospital Universitario de Valladolid

    Valladolid, Spain, Spain

  • Hospital Univesitario y Politénico La Fe

    Valencia, Spain, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Spain, Spain

Conditions

Explore the condition pages connected to this study.