Which antiseptic wins? study tests chlorhexidine vs Povidone-Iodine for thoracoscopy infections

NCT ID NCT05430308

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether cleaning the skin with chlorhexidine-alcohol before a lung procedure (medical thoracoscopy) prevents infections better than the standard povidone-iodine. One hundred patients with undiagnosed fluid around the lung were randomly assigned to one of the two antiseptics. The main goal was to see which one leads to fewer wound or chest infections after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Chlorhexidine scrub and povidone-iodine solution
What this could lead to
If chlorhexidine works better, it could reduce infections after thoracoscopy, making the procedure safer for patients with undiagnosed pleural effusion.
What could go wrong
This is a small, single-center study with only 100 participants, so results may not apply broadly. Both antiseptics are already in use, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bronchoscopy suite

    Chandigarh, Chandigarh, 160012, India

  • Bronchoscopy suite, PGIMER

    Chandigarh, 160012, India

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