Ancient herbal mix may shorten radiation mouth pain in cancer patients

NCT ID NCT07339774

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a traditional Chinese herbal oral solution and mouthwash to see if they can shorten the time head and neck cancer patients suffer from severe mouth sores caused by radiation therapy. About 128 adults aged 18-65 with non-metastatic head and neck cancers will receive either the herbal treatment or a placebo alongside their radiation. The goal is to reduce the duration of painful, severe mucositis (grade 3 or higher) and improve quality of life during treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Zishui Daohuo oral liquid and Kujiu mouthwash (Chinese herbal compound)

What this could lead to

If it works, this could provide a natural option to reduce the time patients suffer from severe mouth sores during radiation therapy.

What could go wrong

This is a small, early-phase trial with only 128 participants, so results may not apply to everyone. Herbal remedies can also cause allergic reactions or interact with other treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced oral mucositis head and neck cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West China Hospital

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••