Ancient herbal mix may shorten radiation mouth pain in cancer patients

NCT ID NCT07339774

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a traditional Chinese herbal oral solution and mouthwash to see if they can shorten the time head and neck cancer patients suffer from severe mouth sores caused by radiation therapy. About 128 adults aged 18-65 with non-metastatic head and neck cancers will receive either the herbal treatment or a placebo alongside their radiation. The goal is to reduce the duration of painful, severe mucositis (grade 3 or higher) and improve quality of life during treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Zishui Daohuo oral liquid and Kujiu mouthwash (Chinese herbal compound)
What this could lead to
If it works, this could provide a natural option to reduce the time patients suffer from severe mouth sores during radiation therapy.
What could go wrong
This is a small, early-phase trial with only 128 participants, so results may not apply to everyone. Herbal remedies can also cause allergic reactions or interact with other treatments.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • West China Hospital

    RECRUITING

    Chengdu, Sichuan, 610041, China

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