Promising new immunotherapies aim to replace harsh chemo for kids with leukemia

NCT ID NCT07476729

First seen May 04, 2026 · Last updated May 04, 2026

Summary

This study tests whether newer, targeted immunotherapy drugs (like inotuzumab and blinatumomab) can replace harsh chemotherapy for children whose B-cell acute lymphoblastic leukemia has returned. About 750 children and teens will receive these less toxic treatments to see if they improve survival and reduce side effects. The goal is to make these immunotherapies the new standard of care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Acıbadem University

    Istanbul, 34752, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de NICE, Hôpital L'ARCHET

    Nice, 06202, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Charité - Universitätsmedizin Berlin

    Berlin, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fakultni Nemocnice V Motole

    Prague, 150 00, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fundeni Clinical Institute, Pediatric Clinic Fundeni

    Bucharest, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ghent University Hospital

    Ghent, B-9000, Belgium

    Contact

  • HUS Helsinki University Hospital

    Helsinki, FIN-00290, Finland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto Português de Oncologia de Lisboa

    Lisbon, 1099-023, Portugal

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Karolinska University Hospital

    Solna, 171 64, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Pediatrico Bambino Gesu

    Rome, 00165, Italy

    Contact

  • Prinses Máxima Centrum

    Utrecht, 3584 CS, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rigshospitalet

    Copenhagen, 2100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Semmelweis University

    Budapest, 1094, Hungary

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Anna Kinderspital GmbH

    Vienna, 1090, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tel Aviv Sourasky Medical Centre Dana-Dwek Children's Hospital

    Tel Aviv, 64239, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Children's Hospital

    Zurich, 8032, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Clinical Hospital Virgen De La Arrixaca

    Murcia, 30120, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Medical Centre Ljubljana

    Ljubljana, 1000, Slovenia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Wroclaw

    Wroclaw, 50 354, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Univerzity Komenského a Národného

    Bratislava, 833 40, Slovakia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.