New hope for kids with tough cancers: testing a powerful drug combo

NCT ID NCT03585465

Summary

This trial is testing whether adding an immunotherapy drug called nivolumab to a specific low-dose chemotherapy regimen can help control cancer in children and teenagers whose solid tumors have come back or didn't respond to standard treatments. The study first checked if the combination was safe, and is now comparing how well the chemotherapy works with and without nivolumab. It aims to find a new treatment option for young patients who have run out of other effective therapies.

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Contacts and locations

Locations

  • Centre Léon Bérard (IHOPe)

    Lyon, France

  • Centre Oscar Lambret

    Lille, France

  • Cliniques Universitaires Saint-Luc (CUSL)

    Brussels, Belgium

  • Hôpital La Timone, AP-HM

    Marseille, France

  • Hôpital Mère-Enfant, CHU Nantes

    Nantes, France

  • Hôpital d'Enfants - CHRU Nancy

    Nancy, France

  • Hôpital de Hautepierre, CHRU Strasbourg

    Strasbourg, France

  • Hôpital des Enfants - CHU Toulouse

    Toulouse, France

  • Institut Curie

    Paris, France

  • University Hospital Ghent

    Ghent, Belgium

  • University Hospital Leuven

    Leuven, Belgium

Conditions

Explore the condition pages connected to this study.