New hope for kids with severe eczema: major trial compares leading treatments

NCT ID NCT06461897

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

Summary

This study aims to see which of two existing drugs works better and is safer for controlling moderate to severe eczema in children aged 2 to 12. About 675 children worldwide will take either a daily pill (upadacitinib) or receive injections every few weeks (dupilumab) for up to three years. Researchers will closely monitor how much the children's skin improves and check for any side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

3A Research - East location /ID# 267622
RECRUITING

El Paso, Texas, 79925, United States
ALERSA, s.r.o. /ID# 266245
RECRUITING

Košice, Košice Region, 040 01, Slovakia
AP-HP - Hopital Necker /ID# 255050
RECRUITING

Paris, 75015, France
Aeroallergy Research Laboratory /ID# 267247
RECRUITING

Savannah, Georgia, 31406, United States
Allergy Research Canada /ID# 270230
RECRUITING

Niagara Falls, Ontario, L2H 1H5, Canada
Amsterdam UMC, locatie AMC /ID# 265406
RECRUITING

Amsterdam, North Holland, 1105 AZ, Netherlands
Applied Research Center Of Arkansas /ID# 268547
RECRUITING

Little Rock, Arkansas, 72205, United States
Arke Smo Sa de Cv /Id# 266650
RECRUITING

Veracruz, 91910, Mexico
Arlington Research Center, Inc /ID# 266330
RECRUITING

Arlington, Texas, 76011, United States
Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 267070
COMPLETED

Rome, Roma, 00161, Italy
Beijing Children's Hospital /ID# 266350
RECRUITING

Beijing, Beijing Municipality, 100045, China
British Columbia Children and Women's Hospital and Health Centre /ID# 265395
RECRUITING

Vancouver, British Columbia, V6H 3N1, Canada
CHU Amiens-Picardie Site Sud /ID# 255083
RECRUITING

Amiens, Somme, 80054, France
CHU Bordeaux - Hopital Pellegrin /ID# 266818
RECRUITING

Bordeaux, Nouvelle-Aquitaine, 33076, France
CHU Toulouse - Hopital Larrey /ID# 255048
RECRUITING

Toulouse, Haute-Garonne, 31400, France
Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois /ID# 265455
RECRUITING

Vandœuvre-lès-Nancy, Meurthe-et-Moselle, 54511, France
Centre Hospitalier Universitaire (CHU) Sainte-Justine /ID# 266831
RECRUITING

Montreal, Quebec, H3T 1C5, Canada
Centre Hospitalier Universitaire de Clermont Ferrand - Hopital Estaing /ID# 267327
RECRUITING

Clermont-Ferrand, Puy-de-Dome, 63100, France
Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu /ID# 265449
RECRUITING

Nantes, Pays de la Loire Region, 44000, France
Centre Hospitalier d Argenteuil Victor Dupouy /ID# 265448
RECRUITING

Argenteuil, Île-de-France Region, 95107, France
Centrum Badan Klinicznych PI-House sp. z o.o. /ID# 265451
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-546, Poland
Centrum Medyczne Angelius Provita /ID# 265456
RECRUITING

Katowice, Silesian Voivodeship, 40-615, Poland
Centrum Nowoczesnych Terapii Dobry Lekarz sp.z.o.o. /ID# 266030
RECRUITING

Krakow, Lesser Poland Voivodeship, 31-011, Poland
Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 267411
RECRUITING

Berlin, 10117, Germany
Chelsea and Westminster Hospital /ID# 266389
RECRUITING

London, Greater London, SW10 9NH, United Kingdom
Chengdu Women and Children Center Hospital /ID# 266402
RECRUITING

Chengdu, Sichuan, 610091, China
Children's Hospital Affiliated to Chongqing Medical University /ID# 266876
RECRUITING

Yuzhong District, Chongqing Municipality, 400015, China
Chungang University Hospital /ID# 266383
RECRUITING

Dongjak-gu, Seoul Teugbyeolsi, 06973, South Korea
Clearlyderm Dermatology - West Boca /ID# 266323
COMPLETED

Boca Raton, Florida, 33428, United States
Cleaver Medical Group Dermatology /ID# 265099
COMPLETED

Dawsonville, Georgia, 30534, United States
Clinica Dermacross /ID# 266309
RECRUITING

Vitacura, Region Metropolitana Santiago, 7640881, Chile
Clinica de Alergia Martti Antila /ID# 266197
RECRUITING

Sorocaba, São Paulo, 18040-425, Brazil
Clinical Research Group Sp. z o.o. /ID# 266924
RECRUITING

Warsaw, Masovian Voivodeship, 01-142, Poland
Clinical Research Investigator Group, LLC /ID# 268366
RECRUITING

Bayamón, 00960, Puerto Rico
Conexa Investigacion Clinica /ID# 268728
RECRUITING

Buenos Aires, 1012, Argentina
Consorci Hospital General Universitario de Valencia /ID# 255289
RECRUITING

Valencia, 46014, Spain
DOCS Clinical Research - Canal Winchester /ID# 268271
RECRUITING

Canal Winchester, Ohio, 43110-2069, United States
Dalian Women and Children's Medical Group /ID# 266675
RECRUITING

Dalian, Liaoning, 116012, China
Dawes Fretzin, LLC /ID# 265097
RECRUITING

Indianapolis, Indiana, 46256, United States
Debreceni Egyetem-Klinikai Kozpont /ID# 265331
RECRUITING

Debrecen, Hajdú-Bihar, 4032, Hungary
DermAssociates - Rockville /ID# 266457
RECRUITING

Rockville, Maryland, 20850, United States
DermAtelier on Avenue /ID# 267850
RECRUITING

Toronto, Ontario, M5M 3Z8, Canada
DermaMed Research - Oroshaza /ID# 266995
RECRUITING

Orosháza, Bekes County, 5900, Hungary
Dermatology Research Institute - Blackfoot Trail /ID# 266744
RECRUITING

Calgary, Alberta, T2J 7E1, Canada
Derriford Hospital and the Royal Eye Infirmary /ID# 266980
RECRUITING

Plymouth, Devon, PL6 8DH, United Kingdom
Equity Medical, LLC /ID# 268270
RECRUITING

Bowling Green, Kentucky, 42104, United States
Erasmus Medisch Centrum /ID# 265408
RECRUITING

Rotterdam, South Holland, 3015 CE, Netherlands
Eukarya PharmaSite /ID# 265274
RECRUITING

Monterrey, Nuevo León, 64718, Mexico
Fachklinik Bad Bentheim /ID# 255165
RECRUITING

Bad Bentheim, Lower Saxony, 48455, Germany
Fakultna nemocnica Trnava /ID# 265245
RECRUITING

Trnava, 917 02, Slovakia
Fundacion Innovacion Cardiovascular /ID# 266742
RECRUITING

Independencia, Santiago Metropolitan, 8380465, Chile
HaEmek Medical Center /ID# 266416
RECRUITING

Afula, Haifa District, 1834111, Israel
Hadassah Medical Center-Hebrew University /ID# 255041
RECRUITING

Jerusalem, Jerusalem, 91120, Israel
Hallym University Kangnam Sacred Heart Hospital /ID# 267318
RECRUITING

Seoul, Seoul Teugbyeolsi, 07441, South Korea
Henan Children's Hospital Zhengzhou Children's Hospital /ID# 266832
RECRUITING

Zhengzhou, Henan, 450018, China
Hospital General Universitario Gregorio Maranon /ID# 255288
RECRUITING

Madrid, 28007, Spain
Hospital Sant Joan de Deu /ID# 255287
RECRUITING

Esplugues de Llobregat, Barcelona, 08950, Spain
Hospital Universitario La Paz /ID# 255286
RECRUITING

Madrid, 28046, Spain
Hospital Universitario Miguel Servet /ID# 255290
RECRUITING

Zaragoza, 50009, Spain
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao /ID# 266667
RECRUITING

São Paulo, 05403-000, Brazil
Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto /ID# 266964
RECRUITING

Ribeirão Preto, São Paulo, 14049-900, Brazil
Hospital e Maternidade Celso Pierro - PUC-Campinas /ID# 266965
RECRUITING

Campinas, São Paulo, 13034-685, Brazil
Hunan Children's Hospital /ID# 266365
RECRUITING

Changsha, Hunan, 410007, China
IRCCS AOU di Bologna Policlinico Sant Orsola Malpighi /ID# 255118
RECRUITING

Bologna, 40138, Italy
Institute for Skin, Health and Immunity /ID# 266158
RECRUITING

Mitcham, Victoria, 3132, Australia
Instituto de Neumonología y Dermatología /ID# 266146
RECRUITING

Buenos Aires, 1425, Argentina
Integrative Skin Science and Research /ID# 265108
RECRUITING

Sacramento, California, 95815, United States
International Clinical Research - Tennessee /ID# 268548
COMPLETED

Murfreesboro, Tennessee, 37130, United States
Irmandade da Santa Casa de Misericórdia de Porto Alegre /ID# 267455
RECRUITING

Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Jordan Valley Dermatology & Research Center /ID# 267092
RECRUITING

South Jordan, Utah, 84095, United States
KK Women's and Children's Hospital /ID# 266519
RECRUITING

Singapore, 229899, Singapore
Kaohsiung Chang Gung Memorial Hospital /ID# 267791
RECRUITING

Kaohsiung City, Kaohsiung, 833, Taiwan
Klinicki Bolnicki Centar KBC Split /ID# 265359
COMPLETED

Split, Split-Dalmatia County, 21000, Croatia
Klinika Ambroziak Dermatologia /ID# 265458
RECRUITING

Warsaw, Masovian Voivodeship, 02-953, Poland
Klinika Osipowicz & Turkowski sp.z.o.o /ID# 267490
RECRUITING

Warsaw, Masovian Voivodeship, 00-716, Poland
Klinika za dječje bolesti Zagreb /ID# 264936
RECRUITING

Zagreb, City of Zagreb, 10000, Croatia
Konkuk University Medical Center /ID# 264178
RECRUITING

Seoul, Seoul Teugbyeolsi, 05030, South Korea
Korea University Ansan Hospital /ID# 264169
RECRUITING

Ansan-si, Gyeonggido, 15355, South Korea
Kunming Childrens Hospital /ID# 266555
RECRUITING

Kunming, Yunnan, 650103, China
Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 265427
RECRUITING

Salzburg, 5020, Austria
Leader Research /ID# 266745
RECRUITING

Hamilton, Ontario, L8L 3C3, Canada
Linkou Chang Gung Memorial Hospital /ID# 263664
RECRUITING

Taoyuan, 333, Taiwan
Lynderm Research Inc /ID# 267006
RECRUITING

Markham, Ontario, L3P 1X2, Canada
MICS Centrum Medyczne Torun / Nasz Lekarz Przychodnie Medyczne /ID# 265454
RECRUITING

Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland
Manchester University NHS Foundation Trust /ID# 267693
RECRUITING

Manchester, M9 2AA, United Kingdom
Maritime Dermatology /ID# 267359
COMPLETED

Halifax, Nova Scotia, B3K 5R3, Canada
Maryland Allergy & Asthma Center /ID# 268032
RECRUITING

Lanham, Maryland, 20706, United States
Medical Center Cordis /ID# 265250
COMPLETED

Pleven, 5800, Bulgaria
Medical University of South Carolina /ID# 265113
RECRUITING

Charleston, South Carolina, 29425, United States
Medizinische Universitaet Graz /ID# 262741
RECRUITING

Graz, Styria, 8010, Austria
Medizinische Universitaet Wien /ID# 265417
RECRUITING

Vienna, 1090, Austria
Monash Health - Monash Medical Centre /ID# 267149
RECRUITING

Clayton, Victoria, 3168, Australia
NZOZ Specjalistyczny Osrodek Dermatologiczny Dermal /ID# 266613
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-453, Poland
Narodny Ustav Detskych Chorob /ID# 265253
RECRUITING

Bratislava, Bratislava Region, 831 01, Slovakia
National Taiwan University Hospital /ID# 265510
RECRUITING

Taipei, 100, Taiwan
National University Hospital /ID# 265685
RECRUITING

Singapore, 119074, Singapore
Neoclinical Research - Hialeah /ID# 269694
COMPLETED

Hialeah, Florida, 33016, United States
New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical /ID# 266349
RECRUITING

New Taipei City, 236, Taiwan
Northwestern University Feinberg School of Medicine /ID# 265117
RECRUITING

Chicago, Illinois, 60611-2927, United States
Oregon Health and Science University /ID# 266483
RECRUITING

Portland, Oregon, 97239, United States
Ospedale Pediatrico Bambino Gesù /ID# 266118
RECRUITING

Rome, Roma, 00165, Italy
Pediatric Skin Research /ID# 266308
RECRUITING

Coral Gables, Florida, 33146, United States
Poliklinika DermaPlus /ID# 265724
RECRUITING

Zagreb, City of Zagreb, 10000, Croatia
Poliklinika Solmed /ID# 265070
RECRUITING

Zagreb, City of Zagreb, 10000, Croatia
Prime Clinical Research - Mansfield - East Broad Street /ID# 268042
RECRUITING

Mansfield, Texas, 76063, United States
Private Practice - Dr. Alma Cruz /ID# 264234
COMPLETED

Carolina, 00985, Puerto Rico
Progressive Clinical Research - San Antonio /ID# 267262
RECRUITING

San Antonio, Texas, 78229, United States

Contact Phone: •••-•••-••••
Psoriahue - Buenos Aires /ID# 267737
RECRUITING

Buenos Aires, 1425, Argentina
Queen Elizabeth University Hospital - NHS Greater Glasgow and Clyde /ID# 265219
RECRUITING

Glasgow, Lanarkshire, G51 4TF, United Kingdom
Rejuvenation Dermatology - Edmonton Downtown /ID# 267871
RECRUITING

Edmonton, Alberta, T5J 3S9, Canada
Royal Victoria Infirmary /ID# 265238
RECRUITING

Newcastle upon Tyne, NE1 4LP, United Kingdom
Royalderm Agnieszka Nawrocka /ID# 266606
RECRUITING

Warsaw, Masovian Voivodeship, 02-962, Poland
Sanatorio 9 de Julio /ID# 267678
RECRUITING

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Schneider Childrens Medical Center of Israel /ID# 265617
RECRUITING

Petah Tikva, Central District, 4920235, Israel
Seoul National University Hospital /ID# 264176
RECRUITING

Seoul, Seoul Teugbyeolsi, 03080, South Korea
Shenzhen Children's Hospital /ID# 266401
RECRUITING

Shenzhen, Guangdong, 518026, China
Skin Specialists /ID# 266331
RECRUITING

Omaha, Nebraska, 68144, United States

Contact Phone: •••-•••-••••
Sneeze Wheeze & Itch Associates /ID# 267238
RECRUITING

Normal, Illinois, 61761, United States
Soon Chun Hyang University Hospital Bucheon /ID# 264171
RECRUITING

Bucheon-si, Gyeonggido, 14584, South Korea
Soroka Medical Center /ID# 265251
RECRUITING

Beersheba, Southern District, 8410101, Israel
Specialty Hospital Medico /ID# 266116
RECRUITING

Rijeka, Primorje-Gorski Kotar County, 51000, Croatia
Specjalistyczny Niepubliczny Zaklad Opieki Zdrowotnej Alergologia Plus /ID# 265457
RECRUITING

Poznan, Greater Poland Voivodeship, 60-693, Poland
St George University Hospitals NHS Foundation Trust /ID# 266984
RECRUITING

London, Greater London, SW17 0QT, United Kingdom
St Thomas' Hospital - Guy's and St Thomas' NHS Foundation Trust /ID# 265237
RECRUITING

London, Greater London, SE1 7EH, United Kingdom
Stanford University School of Medicine - Palo Alto /ID# 269622
RECRUITING

Palo Alto, California, 94304, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont /ID# 265653
COMPLETED

Szeged, Csongrád megye, 6725, Hungary
Taipei Veterans General Hospital /ID# 265507
RECRUITING

Taipei, 112, Taiwan
Texas Dermatology and Laser Specialists /ID# 267249
RECRUITING

San Antonio, Texas, 78218, United States

Contact Phone: •••-•••-••••
The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU /ID# 266708
RECRUITING

Wenzhou, Zhejiang, 325027, China
The Chaim Sheba Medical Center /ID# 265254
RECRUITING

Ramat Gan, Tel Aviv, 5265601, Israel
The Children's Hospital at Westmead /ID# 265430
RECRUITING

Westmead, New South Wales, 2145, Australia
Treasure Valley Medical Research /ID# 266838
RECRUITING

Boise, Idaho, 83706, United States
Triple A Lab Inc /ID# 266615
RECRUITING

Hamilton, Ontario, L8S 1G5, Canada
UMHAT Alexandrovska EAD /ID# 265256
RECRUITING

Sofiya, Sofia, 1431, Bulgaria
Unidade Local de Saude Sao Joao, EPE /ID# 266111
RECRUITING

Porto, 4200-319, Portugal
Unidade Local de Saude de Coimbra, EPE /ID# 266115
RECRUITING

Coimbra, 3000-075, Portugal
Unidade Local de Saude de Santo Antonio, E.P.E. /ID# 266112
RECRUITING

Porto, 4099-003, Portugal
Universitaetsklinikum Carl Gustav Carus Dresden /ID# 255167
RECRUITING

Dresden, Saxony, 01307, Germany
Universitaetsklinikum Erlangen /ID# 255168
RECRUITING

Erlangen, Bavaria, 91054, Germany
Universitaetsklinikum Muenster /ID# 255166
RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany
University Hospital Southampton /ID# 266655
RECRUITING

Southampton, Hampshire, SO16 6YD, United Kingdom
Univerzitna nemocnica L. Pasteura Kosice /ID# 265239
RECRUITING

Košice, Košice Region, 040 01, Slovakia
Univerzitna nemocnica Martin /ID# 265947
RECRUITING

Martin, Žilina Region, 036 01, Slovakia
Washington University School of Medicine - St. Louis /ID# 268545
RECRUITING

St Louis, Missouri, 63130, United States
West Virginia University Hospitals /ID# 265114
RECRUITING

Morgantown, West Virginia, 26506, United States
Wisconsin Medical Center /ID# 267236
RECRUITING

Milwaukee, Wisconsin, 53226, United States

Contact Phone: •••-•••-••••
Wright State Physicians Health Center /ID# 268841
RECRUITING

Fairborn, Ohio, 45324, United States
Xiamen Children's Hospital /ID# 266384
RECRUITING

Xiamen, Fujian, 361006, China

Conditions

Explore the condition pages connected to this study.

ATOPIC DERMATITIS