New pill aims to wipe out lingering lymphoma cells after remission

NCT ID NCT07507318

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 2 trial tests a drug called chidamide in people with a type of aggressive lymphoma (double-expressor DLBCL) who are in remission but still have traces of cancer DNA in their blood. The goal is to see if taking chidamide pills for up to two years can clear those hidden cancer cells and improve long-term outcomes. About 69 adults will take part across multiple hospitals.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Chidamide (a type of targeted cancer pill)

What this could lead to

If successful, this could offer a way to eliminate hidden cancer cells after initial treatment, potentially delaying or preventing relapse in high-risk lymphoma patients.

What could go wrong

This is a small, early-phase study with no control group, so results may not be definitive. Chidamide can cause side effects like low blood counts and fatigue, and not all patients may respond.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma Neoplasm, Residual

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 20000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••