Experimental drug chidamide targets Hard-to-Treat blood cancer

NCT ID NCT05833724

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This phase II trial tests the drug chidamide in people with peripheral T-cell lymphoma that has come back or stopped responding to treatment. The study aims to see if chidamide can shrink tumors and how safe it is. Participants take chidamide twice a week, and doctors monitor their response using scans and clinical exams.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
chidamide (also called Tucidinostat or HBI-8000)
What this could lead to
If successful, chidamide could offer a new treatment option for people with this rare and aggressive blood cancer that has not responded to other therapies.
What could go wrong
This is a small, early-phase trial with only 33 participants, so results may not apply to everyone. The drug may cause side effects and may not shrink tumors in all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chang Gung Memorial Hospital, Kaohsiung

    RECRUITING

    Kaohsiung City, Taiwan

    Contact

  • Chang Gung Memorial Hospital, Linkou

    RECRUITING

    Taoyuan, Taiwan

    Contact

  • Far eastern memorial hospital

    RECRUITING

    New Taipei City, 220, Taiwan

    Contact

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, Taiwan

    Contact

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

    Contact

  • Taichung Veterans General Hospital

    RECRUITING

    Taichung, Taiwan

    Contact

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