New vaccine against rift valley fever shows promise in early trial

NCT ID NCT06799234

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests a new vaccine called ChAdOx1 RVF against Rift Valley fever in 240 healthy adults in Kenya. Participants receive either one or two doses of the vaccine or a rabies vaccine as a control. Researchers will check if the vaccine triggers a strong immune response and monitor for any side effects over 18 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ChAdOx1 RVF vaccine
What this could lead to
If successful, this could lead to a safe and effective vaccine to prevent Rift Valley fever, a serious viral disease.
What could go wrong
This is a Phase 2 trial with only 240 participants, so results may not apply to larger populations. The vaccine may not produce a strong enough immune response or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • KEMRI-Wellcome Trust Research Programme

    Kilifi, Coast, 254, Kenya

More trials for these conditions

Other studies related to the condition(s) this trial covers.