New pill takes aim at hard-to-treat cancers with HER2 mutations
NCT ID NCT07361562
First seen Jan 28, 2026 · Last updated May 18, 2026 · Updated 19 times
Summary
This early-stage study is testing an experimental drug called CGT4255 in about 100 adults whose advanced solid tumors have specific genetic changes (ERBB2 alterations or HER2 overexpression). The main goals are to check safety, find the best dose, and see if the drug shrinks tumors. The study includes people with certain types of lung cancer, breast cancer, and other solid tumors that have spread or cannot be removed by surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NEXT Oncology Texas
RECRUITINGAustin, Texas, 78758, United States
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NEXT Oncology Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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NYU Langone
RECRUITINGNew York, New York, 10016, United States
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
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START Mountain Region
RECRUITINGWest Valley City, Utah, 84119, United States
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Tennessee Oncology
RECRUITINGNashville, Tennessee, 37203, United States
Conditions
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