Nasal cell test may predict cystic fibrosis drug success

NCT ID NCT03894657

First seen Jan 11, 2026 · Last updated May 12, 2026 · Updated 23 times

Summary

This study looked at whether a test using cells from the nose can predict if the drug Orkambi will improve lung function in people with cystic fibrosis. 91 participants with a specific genetic mutation (F508del) took Orkambi for up to 48 weeks. The goal was to see if the lab test matched real-world breathing improvements.

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Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, Île-de-France Region, 75015, France

Conditions

Explore the condition pages connected to this study.