New drug tested for Tough-to-Treat cancers

NCT ID NCT05668585

Summary

This study tested a new drug, CFT1946, for people with advanced solid tumors that have a specific genetic change called BRAF V600. The main goals were to find a safe dose and see if the drug, given alone or with other medications, could help control the cancer. It involved 89 adults whose cancer had worsened after standard treatments.

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Contacts and locations

Locations

  • Allina Health System DBA Virginia Piper Cancer Institute

    Minneapolis, Minnesota, 55407, United States

  • Beatson West of Scotland Cancer Centre

    Glasgow, G12 0YN, United Kingdom

  • Centre Leon Berard

    Lyon, 69008, France

  • Chu de Lille

    Lille, 59037, France

  • Community Health Network

    Indianapolis, Indiana, 46250, United States

  • Complejo Hospitalario de Jaen

    Jaén, 23007, Spain

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center

    New York, New York, 10021, United States

  • Florida Cancer Specialists

    Sarasota, Florida, 34232, United States

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital General Universitario Gregorio Maranon

    Madrid, 28007, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • IUCT Oncopole

    Toulouse, 31059, France

  • Institut Bergonie

    Bordeaux, 33076, France

  • KEM | Evang. Kliniken Essen-Mitte gGmbH

    Essen, 45136, Germany

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • NEXT Oncology Barcelona

    Barcelona, 08023, Spain

  • Sarah Cannon and HCA Research Institute

    Nashville, Tennessee, 37203, United States

  • South Texas Accelerated Research Therapeutics (START) Madrid - Hospital Fundacion Jiminez Diaz

    Madrid, 28040, Spain

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • Universitaetsklinikum Essen

    Essen, 45147, Germany

  • University of Arizona - Cancer Center

    Tucson, Arizona, 85719, United States

  • University of Wisconsin

    Madison, Wisconsin, 53792, United States

  • Virginia Cancer Specialists (NEXT Oncology Virginia)

    Fairfax, Virginia, 22031, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.