New Triple-Threat therapy tested in major cervical cancer trial

NCT ID NCT07216703

Recruiting now Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing a new combination of cancer drugs as a long-term maintenance treatment for women whose cervical cancer has spread and cannot be cured by surgery or radiation. Researchers want to see if adding a new targeted drug (sacituzumab tirumotecan) to existing immunotherapy helps patients live longer or delays the cancer's return compared to standard care. The study will also closely monitor side effects and quality of life for over 1,000 participants.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 1403)
RECRUITING

Chaïdári, Attica, 124 62, Greece

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Alexandra General Hospital of Athens-ONCOLOGY DEPT. ( Site 1401)
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Athens, Attica, 115 28, Greece

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Antwerp University Hospital ( Site 0407)
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Edegem, Antwerpen, 2650, Belgium

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Asan Medical Center ( Site 2904)
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Seoul, 05505, South Korea

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Azienda Ospedaliera Ordine Mauriziano di Torino ( Site 2006)
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Torino, 10128, Italy

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Cancer Institute Hospital of JFCR ( Site 2119)
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Koto, Tokyo, 135-8550, Japan

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Carmel Hospital ( Site 1901)
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Haifa, 3436212, Israel

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Centre Hospitalier de l'Université de Montréal ( Site 0616)
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Montreal, Quebec, H2X 0C1, Canada

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Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0611)
RECRUITING

Québec, Quebec, G1J 1Z4, Canada

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Centro Cancerológico del Caribe (CECAC) ( Site 0906)
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Barranquilla, Atlántico, 080002, Colombia

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Chang Gung Memorial Hospital ( Site 3302)
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Taoyuan District, 333, Taiwan

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Clinica Somer ( Site 0903)
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Rionegro, Antioquia, 054040, Colombia

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Cliniques Universitaires Saint-Luc ( Site 0402)
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Brussels, Bruxelles-Capitale, Region de, 1200, Belgium

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Debreceni Egyetem Klinikai Kozpont ( Site 1601)
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Debrecen, 4032, Hungary

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Fakultni nemocnice Kralovske Vinohrady ( Site 1002)
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Prague, Praha 10, 100 34, Czechia

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Fakultni nemocnice Ostrava ( Site 1005)
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Ostrava, Moravskoslezský kraj, 708 52, Czechia

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Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 2008)
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Milan, Milano, 20133, Italy

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Ginecologia Oncologica ( Site 2012)
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Roma, 00168, Italy

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Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto ( Site 0512)
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São José do Rio Preto, São Paulo, 15091-000, Brazil

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Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0111)
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La Rioja, F5300COE, Argentina

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Fundación Respirar ( Site 0101)
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Belgrano, Buenos Aires F.D., C1118AAT, Argentina

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Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0511)
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Barretos, São Paulo, 14784-400, Brazil

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Grand Hopital de Charleroi ( Site 0404)
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Charleroi, Hainaut, 6060, Belgium

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Hillel Yaffe Medical Center ( Site 1903)
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Hadera, 0038100, Israel

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Hospital Provincial del Centenario ( Site 0106)
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Rosario, Santa Fe Province, S2002KDS, Argentina

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Hospital Ramon y Cajal ( Site 3005)
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Madrid, 28034, Spain

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Hospital São Lucas da PUCRS ( Site 0516)
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Porto Alegre, Rio Grande do Sul, 90610-000, Brazil

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Hospital Universitari Vall d Hebron ( Site 3003)
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Barcelona, 08035, Spain

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Hospital Universitario 12 de Octubre ( Site 3007)
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Madrid, 28041, Spain

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Hospital Universitario La Paz ( Site 3004)
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Madrid, 28046, Spain

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Hospital Universitario Reina Sofia ( Site 3006)
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Córdoba, 14004, Spain

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Hyogo Cancer Center ( Site 2118)
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Akashi, Hyōgo, 673-8558, Japan

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IBCC - Instituto Brasileiro de Controle do Câncer ( Site 0517)
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São Paulo, São Paulo, 04014-002, Brazil

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IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 2009)
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Meldola, Forli-Cesena, 47014, Italy

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Institut Català d'Oncologia (ICO) - Girona ( Site 3002)
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Girona, Gerona, 17007, Spain

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Instituto Nacional De Cancerologia ( Site 0909)
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Bogotá, Bogota D.C., 110411, Colombia

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Instituto de Investigaciones Clinicas Mar del Plata ( Site 0105)
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Mar del Plata, Buenos Aires, B7600FZO, Argentina

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Instituto de Oncologia de Rosario ( Site 0104)
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Rosario, Santa Fe Province, S2000KZE, Argentina

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Istituto Europeo di Oncologia ( Site 2003)
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Milan, 20141, Italy

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Iwate Medical University Hospital ( Site 2116)
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Shiwa-gun, Iwate, 028-3695, Japan

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Karolinska Universitetssjukhuset-Solna ( Site 3102)
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Stockholm, Stockholm County, 171 64, Sweden

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Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 6009)
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New York, New York, 10016, United States

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Linköping University Hospital ( Site 3101)
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Linköping, Östergötland County, 581 85, Sweden

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Mackay Memorial Hospital ( Site 3303)
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Taipei, 10449, Taiwan

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Mazowiecki Szpital Wojewódzki w Siedlcach ( Site 2601)
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Siedlce, Warmian-Masurian Voivodeship, 08-110, Poland

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McGill University Health Centre ( Site 0602)
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Montreal, Quebec, H4A 3J1, Canada

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Mount Sinai Comprehensive Cancer Center ( Site 6000)
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Miami Beach, Florida, 33140, United States

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Narodowy Instytut Onkologii - Oddzial w Gliwicach-III Klinika Radioterapii i Chemioterapii ( Site 2604)
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Gliwice, Silesian Voivodeship, 44-102, Poland

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National Cancer Center ( Site 2905)
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Goyang-si, Kyonggi-do, 10408, South Korea

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National Cheng Kung University Hospital ( Site 3308)
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Tainan, 704, Taiwan

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National Hospital Organization Hokkaido Cancer Center ( Site 2108)
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Sapporo, Hokkaido, 003-0804, Japan

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National Taiwan University Hospital ( Site 3301)
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Taiwan, Taipei, 10002, Taiwan

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Nemocnice AGEL Novy Jicin a.s. ( Site 1004)
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Nový Jičín, Moravskoslezský kraj, 741 01, Czechia

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Niigata Cancer Center Hospital ( Site 2110)
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Niigata, 951-8566, Japan

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Oncology Associates of Oregon, P.C.(Willamette Valley Cancer Institute) (WVCI) ( Site 8007)
RECRUITING

Eugene, Oregon, 97401, United States

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Oncomédica S.A.S ( Site 0905)
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Montería, Departamento de Córdoba, 230002, Colombia

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Oncólogos del Occidente S.A.S. ( Site 0908)
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Pereira, Risaralda Department, 660001, Colombia

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Országos Onkológiai Intézet ( Site 1603)
RECRUITING

Budapest, 1122, Hungary

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Ospedale Cannizzaro ( Site 2010)
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Catania, 95126, Italy

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Ospedale Humanitas San Pio X ( Site 2013)
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Milan, Lombardy, 20159, Italy

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Princess Margaret Cancer Centre ( Site 0601)
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Toronto, Ontario, M5G 2M9, Canada

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Rabin Medical Center ( Site 1904)
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Petah Tikva, 4941492, Israel

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Rambam Health Care Campus ( Site 1907)
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Haifa, 3109601, Israel

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Saitama Medical University International Medical Center ( Site 2106)
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Hidaka, Saitama, 350-1298, Japan

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Samsung Medical Center ( Site 2903)
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Seoul, 06351, South Korea

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Seoul National University Hospital ( Site 2901)
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Jongno-gu, Seoul, 03080, South Korea

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Severance Hospital Yonsei University Health System ( Site 2902)
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Seodaemun-Gu, Seoul, 03722, South Korea

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Shaare Zedek Medical Center ( Site 1905)
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Jerusalem, 9103102, Israel

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Skanes Universitetssjukhus Lund ( Site 3103)
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Lund, Skåne County, 22242, Sweden

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Sourasky Medical Center ( Site 1902)
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Tel Aviv, 6423906, Israel

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Swietokrzyskie Centrum Onkologii. ( Site 2602)
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Kielce, Świętokrzyskie Voivodeship, 25-734, Poland

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TRIALS 365 ( Site 6008)
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Shreveport, Louisiana, 71103, United States

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Taichung Veterans General Hospital ( Site 3304)
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Taichung, 40705, Taiwan

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Texas Oncology - DFW ( Site 8005)
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Fort Worth, Texas, 76104, United States

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Texas Oncology - Northeast Texas ( Site 8002)
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Tyler, Texas, 75702, United States

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UZ Gent ( Site 0406)
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Ghent, Oost-Vlaanderen, 9000, Belgium

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UZ Leuven ( Site 0401)
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Leuven, Vlaams-Brabant, 3000, Belgium

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University of Tennessee Medical Center ( Site 6012)
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Knoxville, Tennessee, 37920, United States

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University of the Ryukyus Hospital ( Site 2117)
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Ginowan, Okinawa, 901-2725, Japan

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Vseobecna fakultni nemocnice v Praze-Gynekologicko-porodnicka klinika 1.LF a VFN ( Site 1001)
RECRUITING

Prague, 128 08, Czechia

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Women's Cancer Center of Nevada ( Site 6011)
RECRUITING

Las Vegas, Nevada, 89106, United States

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Conditions

Explore the condition pages connected to this study.

CERVICAL CANCER