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Shoulder pain study: brain sensitivity may predict injection success

NCT ID NCT05926895

Completed Knowledge-focused Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at 44 people with shoulder pain from rotator cuff tears to see if a condition called central sensitization (where the nervous system is extra sensitive to pain) changes how well a steroid injection works. Participants got a shot of betamethasone and prilocaine into the shoulder, and researchers measured pain and movement. The goal was to find out if those with central sensitization respond differently, which could help tailor treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Betamethasone and prilocaine injection
What this could lead to
If it works, this could help doctors predict which patients will benefit from steroid injections for shoulder pain, leading to more personalized treatment.
What could go wrong
This is a small, completed study (44 people) that only looks for a link, not a treatment. Results may not apply to everyone with shoulder pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rotator cuff syndrome shoulder impingement syndrome Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CENTRAL SENSITISATION SUBACROMIAL IMPINGEMENT SYNDROME

Contacts and locations

Locations

  • Sultan Abdülhamid Han Research and Training Hospital

    Istanbul, Turkey (Türkiye)

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