Scientists implant 'Calming' brain cells to stop uncontrollable seizures
NCT ID NCT06422923
Summary
This early-stage study is testing whether implanting specially engineered 'calming' nerve cells into both sides of the brain can reduce seizures in adults with severe epilepsy that doesn't respond to medications. Ten participants will receive a one-time injection of these cells, which are designed to release a natural chemical that quiets overactive brain circuits. Researchers will monitor safety and track whether seizure frequency decreases over two years of follow-up.
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Atrium Health
RECRUITINGCharlotte, North Carolina, 28204, United States
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Duke University Hospital
RECRUITINGDurham, North Carolina, 27710, United States
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Oregon Health and Science University
RECRUITINGPortland, Oregon, 97239, United States
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SUNY Upstate Medical University
RECRUITINGSyracuse, New York, 13210, United States
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Stanford University
RECRUITINGPalo Alto, California, 94304, United States
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UC Irvine Medical Center
RECRUITINGOrange, California, 92868, United States
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UTHealth Houston
RECRUITINGHouston, Texas, 77030, United States
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UVA Health University Medical Center
RECRUITINGCharlottesville, Virginia, 22903, United States
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University of Arkansas for Medical Sciences
RECRUITINGLittle Rock, Arkansas, 72205, United States
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University of California San Diego
RECRUITINGSan Diego, California, 92037, United States
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University of California San Francisco
WITHDRAWNSan Francisco, California, 94143, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Colorado Anschutz Medical Campus
RECRUITINGAurora, Colorado, 80045, United States
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University of Iowa Health Care
RECRUITINGIowa City, Iowa, 52242, United States
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University of Southern California Keck Hospital
RECRUITINGLos Angeles, California, 90033, United States
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Wake Forest Baptist Medical Center
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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Conditions
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