New cell therapy aims to reduce chemo side effects for rare blood disease

NCT ID NCT04784052

First seen Jan 30, 2026 · Last updated May 14, 2026 · Updated 11 times

Summary

This study tests a new way to treat Fanconi Anemia, a rare genetic disorder that causes bone marrow failure. Instead of standard high-dose chemotherapy, patients receive donor stem cells that have been specially filtered to remove certain immune cells, along with an experimental antibody called JSP191. The goal is to help the donor cells grow in the patient's body with fewer severe side effects. About 18 participants will be followed for up to 2 years after the transplant.

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Contacts and locations

Locations

  • Stanford University

    RECRUITING

    Stanford, California, 94305, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.