Scientists hunt for genetic clues in Barrett's esophagus

NCT ID NCT03316053

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study examines tissue samples from 25 people with Barrett's esophagus (a condition where the lining of the food pipe changes) to find cell and gene changes linked to the disease. Participants provide a small tissue sample during a routine endoscopy. The goal is to better understand the biology of Barrett's esophagus, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could help identify genetic markers that predict progression in Barrett's esophagus, potentially guiding future monitoring or treatment.
What could go wrong
This is a small, observational study with only 25 participants, so findings may not apply broadly. It is not testing a treatment, so no direct benefit to participants.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Guthrie Clinic

    Sayre, Pennsylvania, 18840, United States

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