New shot aims to heal the gut in Tough-to-Treat celiac disease

NCT ID NCT06557772

Ongoing Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

Summary

This study is testing an injectable drug called amlitelimab for adults with celiac disease who still have symptoms and intestinal damage despite following a strict gluten-free diet. The main goal is to see if the drug can help heal the gut lining and reduce symptoms better than a placebo (inactive shot) over 28 weeks. Researchers will also monitor the drug's safety and how the body processes it.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Advanced Research Institute - Denver- Site Number : 8400048

Denver, Colorado, 80218, United States
Advanced Research Institute - Odgen- Site Number : 8400044

Ogden, Utah, 84405, United States
Advanced Research Institute - Reno- Site Number : 8400036

Reno, Nevada, 89511, United States
Advanced Research Institute - Sandy - South 1300 East- Site Number : 8400046

Sandy City, Utah, 84094, United States
Allied Digestive Health - Middlesex Monmouth Gastroenterology- Site Number : 8400053

Freehold, New Jersey, 07728, United States
Azienda Ospedaliera di Padova-Site Number : 3800004

Padua, Padova, 35128, Italy
Berkshire Medical Center- Site Number : 8400017

Pittsfield, Massachusetts, 01201, United States
Boston Specialists- Site Number : 8400051

Boston, Massachusetts, 02111, United States
Center for Digestive Health- Site Number : 8400013

Orlando, Florida, 32803, United States
Centro de Pesquisas da Clínica IBIS- Site Number : 0760006

Salvador, Estado de Bahia, 41820-020, Brazil
Chronos Pesquisa Clínica- Site Number : 0760002

Brasília, Federal District, 72145-450, Brazil
Clinical Research Partners - Richmond - Forest Avenue- Site Number : 8400011

Richmond, Virginia, 23220, United States
DM Clinical Research - Tomball- Site Number : 8400042

Tomball, Texas, 77375, United States
FOMAT Medical Research - inSite Digestive Health Care - Arcadia- Site Number : 8400052

Arcadia, California, 91006, United States
GCP Clinical Research- Site Number : 8400007

Tampa, Florida, 33609, United States
GI Alliance - Tacoma- Site Number : 8400033

Tacoma, Washington, 98405, United States
Gastroenterology Associates of Central Virginia- Site Number : 8400057

Lynchburg, Virginia, 24502, United States
Gastroenterology Associates of Western Michigan - Wyoming- Site Number : 8400004

Wyoming, Michigan, 49519, United States
Hospital Moinhos de Vento- Site Number : 0760004

Porto Alegre, Rio Grande do Sul, 90035-902, Brazil
Hospital Sao Rafael- Site Number : 0760005

Salvador, Estado de Bahia, 41253-190, Brazil
Hospital São Lucas da PUCRS - Porto Alegre - Avenida Ipiranga- Site Number : 0760001

Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Hutchinson Clinic- Site Number : 8400020

Hutchinson, Kansas, 67502, United States
Investigational Site Number : 0320001

Buenos Aires, 1128, Argentina
Investigational Site Number : 0320002

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Investigational Site Number : 0320003

Córdoba, 5000, Argentina
Investigational Site Number : 0320005

Rosario, Santa Fe Province, 2000, Argentina
Investigational Site Number : 0320007

Buenos Aires, 1006, Argentina
Investigational Site Number : 0320008

San Isidro, Buenos Aires, 1642, Argentina
Investigational Site Number : 0320009

Buenos Aires, 1119, Argentina
Investigational Site Number : 0320010

Quilmes, Buenos Aires, 1878, Argentina
Investigational Site Number : 0320012

Buenos Aires, Buenos Aires F.D., 1061, Argentina
Investigational Site Number : 0360001

Mackay, Queensland, 4740, Australia
Investigational Site Number : 0360002

Sydney, New South Wales, 2560, Australia
Investigational Site Number : 0360005

Melbourne, Victoria, 3128, Australia
Investigational Site Number : 0560001

Leuven, 3000, Belgium
Investigational Site Number : 0560002

Brussels, 1200, Belgium
Investigational Site Number : 1240001

Vancouver, British Columbia, V6Z 2K5, Canada
Investigational Site Number : 1240002

Victoria, British Columbia, V8V 3M9, Canada
Investigational Site Number : 1520001

Santiago, Reg Metropolitana de Santiago, 8330034, Chile
Investigational Site Number : 1520004

Santiago, Reg Metropolitana de Santiago, 7620001, Chile
Investigational Site Number : 1520005

Talcahuano, Región del Biobío, 2687000, Chile
Investigational Site Number : 1520006

Concepción, Región del Biobío, 4070038, Chile
Investigational Site Number : 1520007

Santiago, Reg Metropolitana de Santiago, 7510086, Chile
Investigational Site Number : 1520008

Santiago, Reg Metropolitana de Santiago, 8331143, Chile
Investigational Site Number : 2030001

Prague, 118 33, Czechia
Investigational Site Number : 2030002

Brno, 636 00, Czechia
Investigational Site Number : 2030003

Prague, 150 06, Czechia
Investigational Site Number : 2030005

Klatovy, 339 01, Czechia
Investigational Site Number : 2030006

Havířov, 736 01, Czechia
Investigational Site Number : 2460001

Turku, 20520, Finland
Investigational Site Number : 2460002

Helsinki, 00180, Finland
Investigational Site Number : 2460003

Helsinki, 00270, Finland
Investigational Site Number : 2500001

Paris, 75015, France
Investigational Site Number : 2500002

Nice, 06202, France
Investigational Site Number : 2760001

Halle, 06108, Germany
Investigational Site Number : 2760002

Mainz, 55131, Germany
Investigational Site Number : 2760004

Berlin, 12203, Germany
Investigational Site Number : 2760006

Berlin, 10117, Germany
Investigational Site Number : 3000001

Athens, 106 76, Greece
Investigational Site Number : 3000002

Athens, 115 27, Greece
Investigational Site Number : 3760001

Rehovot, 7610001, Israel
Investigational Site Number : 3760002

Afula, 1834111, Israel
Investigational Site Number : 3760003

Petah Tikva, 4941492, Israel
Investigational Site Number : 3760004

Jerusalem, 9103102, Israel
Investigational Site Number : 3760006

Beersheba, 8457108, Israel
Investigational Site Number : 3760007

Ramat HaSharon, 4731001, Israel
Investigational Site Number : 5280001

Amsterdam, 1081 HV, Netherlands
Investigational Site Number : 5280002

Arnhem, 6815 AD, Netherlands
Investigational Site Number : 6160001

Krakow, Lesser Poland Voivodeship, 31-501, Poland
Investigational Site Number : 6160002

Warsaw, Masovian Voivodeship, 02-507, Poland
Investigational Site Number : 6160004

Poznan, Greater Poland Voivodeship, 60-529, Poland
Investigational Site Number : 6160005

Wroclaw, Lower Silesian Voivodeship, 50-088, Poland
Investigational Site Number : 7030001

Košice, 040 13, Slovakia
Investigational Site Number : 7030003

Nitra, 950 01, Slovakia
Investigational Site Number : 7030004

Šahy, 936 01, Slovakia
Investigational Site Number : 7240002

Seville, Sevilla, 41013, Spain
Investigational Site Number : 7240003

Madrid, 28034, Spain
Investigational Site Number : 7240004

Málaga, 29010, Spain
Investigational Site Number : 7240006

Barcelona, Barcelona [Barcelona], 08035, Spain
Investigational Site Number : 7240007

Madrid, 28003, Spain
Investigational Site Number : 7240008

Seville, 41012, Spain
Investigational Site Number : 7240009

Chiclana de la Frontera, Cádiz, 11139, Spain
Investigational Site Number : 7240010

Seville, 41012, Spain
Investigational Site Number : 7240011

Las Palmas de Gran Canaria, Las Palmas, 35010, Spain
Investigational Site Number : 7520001

Uppsala, 752 37, Sweden
Investigational Site Number : 7520003

Stockholm, 116 91, Sweden
Investigational Site Number : 7521001

Mölndal, 431 53, Sweden
Investigational Site Number : 7522001

Linköping, 582 16, Sweden
Investigational Site Number : 7920001

Mersin, 33070, Turkey (Türkiye)
Investigational Site Number : 7920003

Gaziantep, 27310, Turkey (Türkiye)
Investigational Site Number : 7920004

Antalya, 07100, Turkey (Türkiye)
Investigational Site Number : 7920005

Sanliurfa, 63290, Turkey (Türkiye)
Investigational Site Number : 7920006

Istanbul, 34899, Turkey (Türkiye)
Investigational Site Number : 7920007

Izmir, 35100, Turkey (Türkiye)
Investigational Site Number : 8260001

Oxford, Oxfordshire, OX3 9DU, United Kingdom
Investigational Site Number : 8260002

Sheffield, S5 7AU, United Kingdom
LinQ Research - Smith Ranch Road- Site Number : 8400028

Pearland, Texas, 77584, United States
M3 Wake Research - Chattanooga- Site Number : 8400012

Chattanooga, Tennessee, 37421, United States
M3 Wake Research- Site Number : 8400008

Raleigh, North Carolina, 27612, United States
Mayo Clinic in Rochester - Minnesota- Site Number : 8400049

Rochester, Minnesota, 55905, United States
MedCare Pharma - Houston - Cypress Creek Parkway- Site Number : 8400016

Houston, Texas, 77090, United States
Om Research- Site Number : 8400001

Lancaster, California, 93534, United States
Om Research- Site Number : 8400010

Oxnard, California, 93030, United States
One of a Kind Clinical Research Center - Scottsdale- Site Number : 8400055

Scottsdale, Arizona, 85253, United States
Ospedale Maggiore Policlinico Milano-Site Number : 3800002

Milan, Milano, 20122, Italy
Ospedale di Cisanello-Site Number : 3800003

Pisa, 56124, Italy
Praxis Pesquisas Medicas- Site Number : 0760008

Santo André, São Paulo, 09090-790, Brazil
Quality Medical Research- Site Number : 8400018

Nashville, Tennessee, 37211, United States
Sanmora Bespoke Clinical Research Solutions- Site Number : 8400015

East Orange, New Jersey, 07018, United States
Texas Digestive Disease Consultants - Cedar Park- Site Number : 8400030

Cedar Park, Texas, 78613, United States
Thomas Jefferson University Hospital- Site Number : 8400056

Philadelphia, Pennsylvania, 19107, United States
Treasure Valley Medical Research- Site Number : 8400006

Boise, Idaho, 83706, United States
United Medical Doctors - Los Alamitos- Site Number : 8400014

Los Alamitos, California, 90720, United States
University of Kansas Medical Center- Site Number : 8400041

Kansas City, Kansas, 66160, United States
Velocity Clinical Research - Providence- Site Number : 8400002

East Greenwich, Rhode Island, 02818, United States
Velocity Clinical Research - Salt Lake City- Site Number : 8400023

West Jordan, Utah, 84088, United States
Washington University- Site Number : 8400025

St Louis, Missouri, 63110, United States
Wellness Clinical Research - Miami Lakes - 8181 Northwest 154th Street- Site Number : 8400040

Miami Lakes, Florida, 33016, United States

Conditions

Explore the condition pages connected to this study.

CELIAC DISEASE COELIAC DISEASE