Depression breakthrough? Anti-Inflammatory drug targets brain swelling

NCT ID NCT04814355

First seen Apr 25, 2026 · Last updated May 24, 2026 · Updated 1 time

Summary

This study tested whether celecoxib, an anti-inflammatory drug, can reduce brain inflammation in people with major depression. 41 adults with depression received PET scans before and after 8 weeks of celecoxib treatment. The goal was to see if lowering inflammation in key brain areas improves mood symptoms.

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Contacts and locations

Locations

  • Psychiatry Department at Stony Brook University

    Stony Brook, New York, 11794-8101, United States

Conditions

Explore the condition pages connected to this study.