New pain drug shows promise for Post-Surgery relief

NCT ID NCT06423703

Completed Symptom relief Sponsor: Tris Pharma, Inc. Source: ClinicalTrials.gov ↗

First seen Jan 10, 2026 · Last updated May 12, 2026 · Updated 24 times

Summary

This study tested a new pain medication called cebranopadol in 240 adults who had bunion surgery. The goal was to see if it safely reduces moderate to severe acute pain better than a placebo or an active comparator. Participants were randomly assigned to receive the drug, a placebo, or another painkiller, and their pain levels and need for extra rescue medication were measured.

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Contacts and locations

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Locations

ALLEVIATE 2 Site 001101

Salt Lake City, Utah, 84107, United States
ALLEVIATE 2 Site 001102

Atlanta, Georgia, 30331, United States
ALLEVIATE 2 Site 001103

Tampa, Florida, 33613, United States
ALLEVIATE 2 Site 001104

McAllen, Texas, 78501, United States
ALLEVIATE 2 Site 001105

Pasadena, Maryland, 21122, United States
ALLEVIATE 2 Site 001106

Little Rock, Arkansas, 72211, United States
ALLEVIATE 2 Site 001107

Overland Park, Kansas, 66212, United States
ALLEVIATE 2 Site 001108

Sheffield, Alabama, 35660, United States
ALLEVIATE 2 Site 001111

San Antonio, Texas, 78240, United States
Alleviate 2 001113

Houston, Texas, 77043, United States

Conditions

Explore the condition pages connected to this study.

ACUTE PAIN