New combo therapy aims to stop High-Risk breast cancer from coming back

NCT ID NCT07019363

First seen Jan 22, 2026 · Last updated May 24, 2026 · Updated 16 times

Summary

This study tests whether adding a CDK4/6 inhibitor to standard hormone therapy can help prevent breast cancer from returning in women with a high-risk, hormone receptor-positive and HER2-positive early breast cancer who have already completed anti-HER2 treatment. About 1,900 women aged 18 to 70 will be randomly assigned to receive either the standard therapy alone or with the added drug. The main goal is to see if the combination improves survival without cancer recurrence over five years.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Fudan cancer center

    RECRUITING

    Shanghai, China

Conditions

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