Massive gene hunt launched to unlock secrets of rare birth defect

NCT ID NCT00950118

First seen Dec 16, 2025 · Last updated May 13, 2026 · Updated 18 times

Summary

This study aims to find the genes that make a baby more likely to be born with a congenital diaphragmatic hernia (CDH), a hole in the muscle that separates the chest from the belly. Researchers will collect DNA samples from 3,000 people with CDH and their families to look for genetic causes. The goal is to better understand the disease and, in the future, find ways to prevent or treat it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Cairo University Hospital

    RECRUITING

    Cairo, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital of Omaha/ University of Nebraska

    RECRUITING

    Omaha, Nebraska, 68114, United States

    Contact

    Contact Email: •••••@•••••

  • Children's Hospital of Pittsburgh/ University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Cincinnati Children's Hospital and Medical Center/ University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical College of Wisconsin

    COMPLETED

    Milwaukee, Wisconsin, 53226, United States

  • Monroe Carrell Jr Children's Hospital at Vanderbilt

    COMPLETED

    Nashville, Tennessee, 37232, United States

  • Morgan Stanley Children's Hospital of New York- Presbyterian (Columbia University Medical Center)

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • New York University, Hassenfeld Children's Hospital at NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact

  • Northwell Health

    RECRUITING

    Manhasset, New York, 11030, United States

    Contact Email: •••••@•••••

    Contact

  • Oregon Health & Science University, Doernbecher Children's Hospital

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Rush Hospital

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact

    Contact

  • UT Southwestern Medical Center, Children's Health, Dallas

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan/ CS Mott Children's Hospital

    RECRUITING

    Ann Arbor, Michigan, 48167-5245, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University Medical Center/ St. Louis Children's Hospital

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.