Engineered immune cells take aim at Hard-to-Treat leukemia

NCT ID NCT06871410

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 23 times

Summary

This early-phase trial tests a new treatment using specially engineered immune cells (CD83 CAR T cells) for adults with acute myeloid leukemia (AML) that has returned or not responded to standard therapy. The cells are designed to find and destroy leukemia cells while reducing the risk of serious side effects like graft-versus-host disease. The study will enroll 26 participants to evaluate safety, find the best dose, and check for early signs of effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

Explore the condition pages connected to this study.