Engineered immune cells take on deadly brain cancer in first human test

NCT ID NCT06946680

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 20 times

Summary

This early-phase study tests whether a new type of immune cell therapy is safe and possible to make for people with aggressive brain tumors called high-grade gliomas. The therapy uses a patient's own immune cells, modified to recognize and attack tumor cells that carry a specific marker (CD70). The study involves 18 participants and focuses on finding the right dose and checking for severe side effects.

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Contacts and locations

Locations

  • University of Florida Health Children's Hospital

    Gainesville, Florida, 32608, United States

Conditions

Explore the condition pages connected to this study.