Could a One-Time cell therapy free patients from lifelong autoimmune drugs?

NCT ID NCT06680388

First seen Jan 03, 2026 · Last updated May 01, 2026 · Updated 20 times

Summary

This early-phase study tests a personalized cell therapy (CD19 CAR-T) in 15 adults with severe autoimmune diseases like lupus that have not responded to standard treatments. The therapy aims to reset the immune system by targeting and depleting faulty B cells, potentially reducing or eliminating the need for lifelong medication. The main goals are to check safety and see if the treatment can control the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chinese Academy of Medical Sciences Hospital of Hematology (Chinese Academy of Medical Sciences Institute of Hematology), Tianjin, 300020

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

Conditions

Explore the condition pages connected to this study.