Immune cell therapy shows promise for tough lymphoma cases

NCT ID NCT03029338

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested a personalized cell therapy called CD19 CAR T cells in 20 adults with relapsed or refractory B-cell lymphoma. The treatment involves taking a patient's own immune cells, engineering them to recognize and attack cancer cells, and infusing them back. The main goals were to check safety and see if the cells could shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CD19 CAR T cells (a type of immune cell therapy)

What this could lead to

If successful, this could point toward a new treatment option for people with hard-to-treat B-cell lymphoma.

What could go wrong

This is a very early Phase 1 trial with only 20 participants, so results may not apply to everyone. Side effects from CAR T therapy can be serious.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell neoplasm B-cell non-Hodgkin lymphoma lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institute of Hematology & Blood Diseases Hospital

    Tianjin, 300020, China