Engineered t cells take aim at Hard-to-Treat leukemias

NCT ID NCT02159495

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 24 times

Summary

This early-phase study tests a new type of immunotherapy for people with certain leukemias that have come back or not responded to standard treatments. The therapy uses a patient's own or a donor's immune cells that are genetically modified to recognize and attack cancer cells carrying a protein called CD123. The main goals are to find the safest dose and to see if the treatment can shrink or eliminate the cancer.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.