New combo aims to stop leukemia relapse after transplant
NCT ID NCT06498973
First seen Mar 06, 2026 · Last updated May 16, 2026 · Updated 10 times
Summary
This early-phase trial tests whether combining tagraxofusp (a targeted therapy) with azacitidine (a chemotherapy-like drug) can safely prevent acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) from coming back after a donor stem cell transplant. About 43 adults aged 18–75 with CD123-positive disease will receive the drug combination as maintenance therapy. The main goals are to find the best dose and check for side effects.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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