New shot aims to melt belly fat without surgery

NCT ID NCT07526974

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests an injection called CBL-514 to see if it can safely reduce belly fat. About 320 adults with moderate to severe abdominal fat will receive either the drug or a placebo. The main goal is to see if more people in the drug group report a meaningful fat reduction compared to those getting the placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CBL-514 injection
What this could lead to
If it works, this could offer a non-surgical option to reduce belly fat in people who are not overweight.
What could go wrong
This is a cosmetic treatment, not a cure for any disease. Results may be modest, and side effects from the injection are possible. The trial is not yet recruiting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site 1

    Encinitas, California, 92024, United States

  • Investigational Site 10

    Arlington, Virginia, 22209, United States

  • Investigational Site 11

    Seattle, Washington, 98109, United States

  • Investigational Site 13

    Vancouver, British Columbia, V5Z 1H2, Canada

  • Investigational Site 14

    Woodbridge, Ontario, L4L 8E2, Canada

  • Investigational Site 3

    Alpharetta, Georgia, 30005, United States

  • Investigational Site 4

    Hunt Valley, Maryland, 21030, United States

  • Investigational Site 7

    Canal Winchester, Ohio, 43110, United States

  • Investigational site 12

    Melbourne, Victoria, 3141, Australia

  • Investigational site 2

    Aventura, Florida, 33180, United States

  • Investigational site 5

    Omaha, Nebraska, 68144, United States

  • Investigational site 6

    New York, New York, 10028, United States

  • Investigational site 8

    Nashville, Tennessee, 37215, United States

  • Investigational site 9

    Austin, Texas, 78759, United States

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