Belly fat melting shot? phase 3 trial begins.

NCT ID NCT07140939

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether an injection called CBL-514 can safely reduce abdominal fat. 300 adults with moderate to severe belly fat will receive either the drug or a placebo. The study measures fat loss by MRI and patient ratings over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CBL-514 injection
What this could lead to
If it works, this could offer a non-surgical way to reduce stubborn belly fat.
What could go wrong
This is an early Phase 3 trial, so results are not yet known. The treatment may not work better than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SUBCUTANEOUS FAT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational site 1

    Encinitas, California, 92024, United States

  • Investigational site 10

    Nashville, Tennessee, 37215, United States

  • Investigational site 11

    Pflugerville, Texas, 78660, United States

  • Investigational site 12

    Vancouver, British Columbia, V5Z1H4, Canada

  • Investigational site 13

    Toronto, Ontario, M4W2N4, Canada

  • Investigational site 2

    West Palm Beach, Florida, 33401, United States

  • Investigational site 3

    Chicago, Illinois, 60610, United States

  • Investigational site 4

    Baton Rouge, Louisiana, 70809, United States

  • Investigational site 5

    Hunt Valley, Maryland, 21030, United States

  • Investigational site 6

    Omaha, Nebraska, 68144, United States

  • Investigational site 7

    Hackensack, New Jersey, 07601, United States

  • Investigational site 8

    New York, New York, 10028, United States

  • Investigational site 9

    Charlotte, North Carolina, 28207, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.