Scientists watch for clues to predict transplant complication

NCT ID NCT04188912

Completed Knowledge-focused Sponsor: Fred Hutchinson Cancer Center Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This study followed 267 adults before and after stem cell transplants to understand why some develop chronic graft-versus-host disease (GVHD), a common complication. Researchers collected blood, saliva, and eye fluid samples and performed tests to spot early signs. The goal is to predict who will get chronic GVHD and catch it sooner.

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Contacts and locations

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Locations

Cleveland Clinic

Cleveland, Ohio, 44195, United States
Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, 98109, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
National Cancer Institute

Bethesda, Maryland, 20892, United States
Roswell Park

Buffalo, New York, 14263, United States
University of Florida

Gainesville, Florida, 32610, United States
Vanderbilt

Nashville, Tennessee, 37212, United States

Conditions

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HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM