New cell therapy trial targets toughest childhood leukemias

NCT ID NCT04276870

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 35 times

Summary

This study tests a personalized cell therapy (CART19) in children and young adults with rare, high-risk forms of B-cell acute lymphoblastic leukemia (B-ALL). The treatment uses the patient's own immune cells, modified to find and kill cancer cells. The goal is to see if this therapy can improve survival and control the disease in patients who have limited options.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

B-cell childhood acute lymphoblastic leukemia B-lymphoblastic leukemia/lymphoma with hypodiploidy B-lymphoblastic leukemia/lymphoma with t(17;19) B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) central nervous system leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.