New chemo formula could cut side effects in lymphoma transplants
NCT ID NCT06915246
First seen Apr 01, 2026 · Last updated Jun 20, 2026 · Updated 10 times
Summary
This phase 2 trial is testing a new formulation of the chemotherapy drug carmustine that doesn't contain ethanol, compared to the standard version that does. Both are used as part of the BEAM conditioning regimen before an autologous stem cell transplant in adults with Hodgkin or non-Hodgkin lymphoma. The study aims to see if the ethanol-free version causes fewer infusion-related and other serious side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LYMPHOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
City of Hope Atlanta
RECRUITINGNewnan, Georgia, 30265, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
City of Hope Chicago
RECRUITINGZion, Illinois, 60099, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
City of Hope National Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
City of Hope Phoenix
RECRUITINGGoodyear, Arizona, 85338, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
carmustine
What this could lead to
If successful, this could offer a safer version of a standard chemotherapy drug used in stem cell transplants for lymphoma, reducing side effects from the ethanol solvent.
What could go wrong
This is an early phase 2 trial with only 49 participants, so results may not apply broadly. The new formulation might not reduce toxicities as hoped, or could have unexpected risks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.