Blood test could replace surgery for heart tumor diagnosis

NCT ID NCT07235865

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing whether a blood test, called a liquid biopsy, can accurately diagnose and monitor heart masses (tumors) without needing a surgical biopsy. Researchers will collect blood samples from 26 patients aged 12 and older with suspected or confirmed cardiac masses. They will analyze the blood for tumor DNA and compare results with standard tissue samples. If the blood test works, it could offer a safer, less invasive way to diagnose and track heart tumors over time.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Liquid biopsy (blood test for ctDNA)
What this could lead to
If successful, this could provide a non-invasive way to diagnose and monitor heart tumors, potentially reducing the need for risky biopsies or surgeries.
What could go wrong
This is a small, early observational study with only 26 participants. The blood test may not be accurate enough to replace standard diagnostic methods, and results may not apply to all types of cardiac masses.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Niguarda Hospital

    RECRUITING

    Milan, Italia, 20262, Italy

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