Which fluid best shields the heart during bypass? new study aims to find out

NCT ID NCT07358221

Not yet recruiting Knowledge-focused Sponsor: Damascus University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will compare three different fluids used to protect the heart during coronary artery bypass surgery. Researchers will measure tiny particles and immune system markers in the blood to see which fluid causes the least heart muscle injury. The goal is to find the safest approach for patients undergoing this common heart procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cardioplegia solutions (St. Thomas' cold crystalloid, Calafiore warm blood, modified del Nido cold blood)
What this could lead to: If successful, this could help surgeons choose the best heart-protection method during bypass surgery, potentially reducing heart damage.
What could go wrong: This is a small, early-stage observational study (30 people) that measures biological markers, not patient outcomes. The results may not change practice directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY BYPASS GRAFTING (CABG) SURGERY MYOCARDIAL PROTECTION

Contacts and locations

Locations

Damascus University Cardiac Surgery Hospital

Damascus, Rif-dimashq Governorate, Rawda, Syria

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