New drug duo aims to stop kidney transplant rejection

NCT ID NCT06918990

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 30 times

Summary

This study tests two drugs, carfilzomib and belatacept, along with standard steroids and immune-suppressing medicines, in 25 kidney transplant patients who have signs of rejection. The goal is to see if this combination is safe and can reduce harmful antibodies that attack the new kidney. Participants will be monitored for a year with regular biopsies and blood tests.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University

    NOT_YET_RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Arizona

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern University, Feinberg School of Medicine

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Medical Center (Site #: 71123)

    NOT_YET_RECRUITING

    Los Angeles, California, 90024, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alabama Medical Center

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Cincinnati

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Wisconsin - Madison

    NOT_YET_RECRUITING

    Madison, Wisconsin, 53726, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.