New cell therapy tested for Tough-to-Treat blood cancer

NCT ID NCT03601078

First seen Mar 12, 2026 · Last updated Apr 20, 2026 · Updated 3 times

Summary

This study tested an experimental cell therapy called bb2121 for people with multiple myeloma, a blood cancer, that had come back after treatment or was considered high-risk. The therapy involves modifying a patient's own immune cells to attack the cancer. Researchers aimed to see how well it worked and how safe it was for different groups of patients.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Clinica Universidad de Navarra

    Pamplona, 31008, Spain

  • Columbia University Medical Center/New York-Presbyterian Hospital

    New York, New York, 10032, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215-5450, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30322, United States

  • Froedtert Hospital BMT Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • John Theurer Cancer Center at Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Kings College Hospital NHS Foundation Trust

    London, SE5 9RS, United Kingdom

  • Levine Cancer Institute

    Charlotte, North Carolina, 28204, United States

  • Local Institution - 404

    Poitiers, 86021, France

  • Local Institution - 505

    Würzburg, 97080, Germany

  • Local Institution - 506

    Hamburg, 20246, Germany

  • Local Institution - 603

    Bologna, 40138, Italy

  • Local Institution - 704

    Salamanca, 37007, Spain

  • MD Anderson Cancer Center The University of Texas

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02117, United States

  • Mayo Clinic in Arizona - Scottsdale

    Scottsdale, Arizona, 85259, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Mt Sinai Medical Center - NY

    New York, New York, 10029, United States

  • Swedish Cancer Inst

    Seattle, Washington, 98104, United States

  • Tennessee Oncology PLLC

    Nashville, Tennessee, 37203, United States

  • University Of California San Francisco Medical Center

    San Francisco, California, 94143, United States

  • University Of Nebraska

    Omaha, Nebraska, 68198-7680, United States

  • University Of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.