Scientists test revolutionary 'Living Drug' for incurable autoimmune diseases
NCT ID NCT06544330
Summary
This early-stage study is testing the safety of a new two-part cell therapy (SYNCAR-001 + STK-009) in adults with severe forms of lupus or scleroderma that haven't responded to other treatments. The therapy involves collecting and modifying a patient's own immune cells (CAR-T cells) to target the disease, followed by injections of a supporting drug. The main goal is to see if this approach is safe and tolerable, while also checking if it helps control these difficult autoimmune conditions.
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Contacts and locations
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Locations
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Feinstein Institutes for Medical Research
Manhasset, New York, 11030, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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HonorHealth Research Institute
Scottsdale, Arizona, 85258, United States
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Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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The Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
Conditions
Explore the condition pages connected to this study.