Engineered immune cells target hard-to-treat blood cancer
NCT ID NCT05396885
First seen Nov 16, 2025 · Last updated Apr 25, 2026 · Updated 23 times
Summary
This study tests a new treatment called CART-ddBCMA for people with multiple myeloma that has come back or not responded to at least three prior therapies. The therapy uses a patient's own immune cells, modified to attack cancer cells carrying a protein called BCMA. The main goal is to see how many patients respond to treatment, with 136 adults expected to take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Colorado Blood Cancer Institute
Denver, Colorado, 80218, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Froedtert Hospital & the Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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HonorHealth Cancer Transplant Institute
Scottsdale, Arizona, 85258, United States
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Huntsman Cancer Institute, University of Utah
Salt Lake City, Utah, 84112, United States
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John Theurer Cancer Center at Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Levine Cancer Institute
Charlotte, North Carolina, 28204, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Northside Hospital
Atlanta, Georgia, 30342, United States
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Oregon Health & Science University (OHSU)
Portland, Oregon, 97239, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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University of Maryland Greenebaum Comprehensive Cancer Center
Baltimore, Maryland, 21201, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Wisconsin Clinical Science Center
Madison, Wisconsin, 53792, United States
Conditions
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