Immune cell overhaul: could CAR-T tame tough lupus?

NCT ID NCT07403097

First seen Feb 17, 2026 · Last updated May 12, 2026 · Updated 11 times

Summary

This early-phase study tests a personalized cell therapy (CAR-T) for people with severe lupus that hasn't responded to standard treatments. The therapy uses the patient's own immune cells, modified to target and calm overactive B cells. The goal is to reduce disease activity and improve symptoms, but ongoing medication may still be needed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SYSTEMIC LUPUS ERYTHEMATOSUS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.