Engineered immune cells take aim at lupus in new clinical trial

NCT ID NCT06897930

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 25 times

Summary

This study tests a new treatment called AZD0120 for adults with severe lupus that hasn't improved with standard therapies. AZD0120 uses a patient's own immune cells, modified to target and destroy faulty cells that drive lupus. The trial will check safety and whether it can reduce lupus symptoms, but ongoing medication may still be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    NOT_YET_RECRUITING

    San Francisco, California, 94143, United States

  • Research Site

    NOT_YET_RECRUITING

    Stanford, California, 94304-2201, United States

  • Research Site

    SUSPENDED

    Tampa, Florida, 33612, United States

  • Research Site

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

  • Research Site

    WITHDRAWN

    Bethesda, Maryland, 20892, United States

  • Research Site

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

  • Research Site

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

  • Research Site

    RECRUITING

    New York, New York, 10032, United States

  • Research Site

    RECRUITING

    Syracuse, New York, 13202-2240, United States

  • Research Site

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27599-7280, United States

  • Research Site

    RECRUITING

    Charlotte, North Carolina, 28204, United States

  • Research Site

    NOT_YET_RECRUITING

    Richmond, Virginia, 23298, United States

  • Research Site

    NOT_YET_RECRUITING

    Seattle, Washington, 98104, United States

  • Research Site

    RECRUITING

    Seattle, Washington, 98195, United States

  • Research Site

    NOT_YET_RECRUITING

    Darlinghurst, 2010, Australia

  • Research Site

    NOT_YET_RECRUITING

    Melbourne, 3000, Australia

Conditions

Explore the condition pages connected to this study.