Engineered immune cells show promise against tough leukemia

NCT ID NCT06481735

First seen Nov 19, 2025 · Last updated May 15, 2026 · Updated 21 times

Summary

This study tests a new type of CAR-T cell therapy for adults with B-cell acute lymphoblastic leukemia that has come back or not responded to treatment. The therapy uses donor immune cells that are modified to better target and kill cancer cells while reducing side effects like graft-versus-host disease. The goal is to see if this approach is safe and effective, with about 30 participants taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Biotherapeutic Department of Chinese PLA General Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100853, China

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Department of Hematology, Chinese PLA General Hospital

    RECRUITING

    Beijing, China

    Contact

    Contact

    Contact

    Contact

    Contact

  • Department of Hematology, Heping Hospital Affiliated to Changzhi Medical College

    RECRUITING

    Changzhi, China

    Contact

  • Department of Hematology, Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Hematology, Tianjin First Central Hospital

    RECRUITING

    Tianjin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Immune Cell Therapy Center, Blood Disease Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Tianjin, China

    Contact

Conditions

Explore the condition pages connected to this study.