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Engineered immune cells take on childhood arthritis and autoimmune diseases

NCT ID NCT07184450

Recruiting now Disease control Sponsor: Chongqing Precision Biotech Co., Ltd Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This early-stage study is testing a new treatment using specially engineered immune cells (CAR-T cells) in 11 children with severe rheumatic diseases like juvenile dermatomyositis, arthritis, and scleroderma that haven't responded to standard therapies. The goal is to see if these cells can safely reduce disease activity and improve symptoms. Because these are chronic autoimmune conditions, the treatment aims to control the disease rather than provide a permanent cure.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

JUVENILE DERMATOMYOSITIS (JDM) POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS PRIMARY SJOGREN'S SYNDROME SYSTEMIC SCLEROSIS (SSC) SYSTEMIC SCLEROSIS (SSC)