Engineered immune cells take on brain cancer in early trial

NCT ID NCT07555561

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a new treatment for patients with relapsed or hard-to-treat lymphoma in the brain or spinal cord. The therapy uses the patient's own immune cells, modified to recognize and attack cancer cells. The main goals are to check safety and see if the treatment can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
A patient's own immune cells (T cells) are modified in a lab to recognize and attack lymphoma cells in the brain and spinal cord.
What this could lead to
If it works, this could offer a new treatment option for patients with hard-to-treat lymphoma in the central nervous system.
What could go wrong
This is a very early (phase 1) and small trial (30 people), so it may not show clear benefit. The therapy also carries risks like severe immune reactions or brain swelling.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing GoBroad Boren Hospital

    Beijing, Fengtai District, 100070, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.