One-Shot cell therapy aims to reset immune system in devastating scleroderma

NCT ID NCT07493395

Summary

This early-stage trial is testing whether a single infusion of a patient's own genetically modified immune cells (CAR T-cells) can reduce disease activity in adults with severe systemic sclerosis (scleroderma) that hasn't responded to other treatments. The study will enroll 6 participants to primarily check if the therapy is safe and if it improves skin thickening and other symptoms. Patients will be closely monitored for two years after the one-time infusion to see how their bodies respond.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP Necker

    Paris, France

    Contact

    Contact Email: •••••@•••••

  • CHRU Lille

    Lille, France

    Contact Email: •••••@•••••

    Contact

  • Chu Rouen

    Rouen, France

    Contact Email: •••••@•••••

  • Montpellier University Hospital

    Montpellier, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.